Company

Alfasigma

As of the edition of 20 October 2026, Alfasigma runs 10 drugs, 5 of them marketed; it is on route A at 0 targets and on route B at 2 targets.

Sources: ClinicalTrials.gov, FDA Orange Book and Purple Book, other approval registers, company records.

Family history

The records place 4 company names in this family.

  • Intercept Pharmaceuticals: acquired in 2023
  • SOFAR S.p.A.: acquired in 2023; successor Alfasigma S.p.A.

Drugs by status

StatusCount
Marketed5
Active1
Went quiet1
Stopped2
Withdrawn from market1
Total10

Marketed drugs and when their US protection ends

DrugUS protectionRoute B rows
Filgotinibnone listed3
Obeticholic acidEnds 2033 (patent)1
Piperaquinenone listed0
Artenimolnone listed0
LinerixibatEnds 2033 (exclusivity)1

A route B row is one company at one target.

Where it needs a new molecule

Route A at 0 targets, route B at 2 targets.

Three of its 2 rows, by target and route
TargetRoute
SLC10A2 Ileal sodium/bile acid cotransporterRoute B
NR1H4 Bile acid receptorRoute B

All 2 rows on route A or B

In the product

2 company-target rows on route A or B; 0 are not shown here, and no score is.

Where its trials are

  • Digestive system: 15 trials led
  • Immune system: 3 trials led
  • Blood and lymph: 1 trials led