PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
As of the edition of 20 October 2026, PIK3CD (phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, UniProt O00329) has 49 drugs tested at it and 48 companies on the list, 27 on route A and 5 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- O00329
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 20
- Disease areas
- Cancer; Blood and lymph; Immune system; Skin and connective tissue; Lungs and airways; Urinary and reproductive; Nervous system; Pregnancy and women's health
- Registered trials of its drugs
- 626
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 5 |
| Active | 7 |
| Went quiet | 15 |
| Stopped | 17 |
| Withdrawn from market | 1 |
| Status not established | 4 |
| Total | 49 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Buparlisib | Stopped | Phase 3 | none listed |
| Copanlisib | Marketed | Phase 3 | Ends 2032 |
| Idelalisib | Marketed | Phase 4 | Ends 2033 |
| Duvelisib | Marketed | Phase 3 | Ends 2032 |
| Parsaclisib | Active | Phase 3 | none listed |
| Umbralisib | Withdrawn from market | Phase 3 | Ends 2035 |
| Dactolisib | Went quiet | Phase 3 | none listed |
| Linperlisib | Active | Phase 4 | none listed |
| Gedatolisib | Marketed | Phase 3 | Ends 2031 |
| Samotolisib | Stopped | Phase 2 | none listed |
| Pictilisib | Went quiet | Phase 2 | none listed |
| Taselisib | Stopped | Phase 3 | none listed |
12 of 49 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 27 |
| Route B | 5 |
| Engaged | 12 |
| Undetermined | 4 |
| Total on the list | 48 |
| Company | Route |
|---|---|
| Gilead Sciences | Route B |
| GSK | Route A |
| Amgen | Route A |
The other 45 companies at PIK3CD
In the product48 companies in all; 45 are not named here, and no score is.
See the 48 companies at PIK3CD, ranked, with the facts behind eachRequest access. Nothing is shown until you do.