Merck & Co.
As of the edition of 20 October 2026, Merck & Co. runs 514 drugs, 198 of them marketed; it is on route A at 73 targets and on route B at 43 targets.
Sources: ClinicalTrials.gov, FDA Orange Book and Purple Book, other approval registers, company records.
Family history
Merck & Co. was renamed in 2008.
The records place 28 company names in this family.
- Merck Sharp & Dohme LLC: renamed in 2008
Drugs by status
| Status | Count |
|---|---|
| Marketed | 198 |
| Active | 58 |
| Went quiet | 123 |
| Stopped | 103 |
| Withdrawn from market | 1 |
| Status not established | 31 |
| Total | 514 |
Marketed drugs and when their US protection ends
| Drug | US protection | Route B rows |
|---|---|---|
| Dexamethasone | none listed | 5 |
| Pembrolizumab | Ends 2031 (orphan exclusivity) | 1 |
| Metformin | none listed | 4 |
| Prednisone | none listed | 1 |
| Cetuximab | Ended 2016 (computed from the first US licence) | 2 |
| Temozolomide | none listed | 0 |
| Atorvastatin | none listed | 4 |
| Ribavirin | none listed | 1 |
| Rosuvastatin | none listed | 3 |
| Lamivudine | none listed | 0 |
| Simvastatin | none listed | 3 |
| Prednisolone | none listed | 6 |
| Tenofovir disoproxil | none listed | 0 |
| Omeprazole | none listed | 2 |
| Sitagliptin | Ends 2026 (patent) | 1 |
| Somatropin | Ended 2003 (orphan exclusivity) | 4 |
| Ezetimibe | none listed | 3 |
| Hydrocortisone | none listed | 5 |
| Albuterol | none listed | 2 |
| Vorinostat | Ends 2027 (patent) | 4 |
| Losartan | none listed | 1 |
| Progesterone | none listed | 3 |
| Hydrochlorothiazide | none listed | 4 |
| Peginterferon alfa-2b | Ended 2013 (computed from the first US licence) | 0 |
| Ethinyl estradiol | none listed | 5 |
A route B row is one company at one target. 173 more marketed drugs are not listed here.
Where it needs a new molecule
Route A at 73 targets, route B at 43 targets.
All 116 rows on route A or B
In the product116 company-target rows on route A or B; 113 are not shown here, and no score is.
See all 116 targets where Merck & Co. needs a new molecule, with the facts behind eachRequest access. Nothing is shown until you do.
Where its trials are
- Cancer: 354 trials led
- Infections: 307 trials led
- Urinary and reproductive: 213 trials led