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20 October 2026

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Drugs · companies · targets · areas · years
US protection by year

Marketed drugs, by the year their US protection ends

The year of the latest counted date, not the date generics or biosimilars can enter. Marked computed where it is worked out from the first US licence.

DrugKind of dateHolderTargetCompanies with no follow-on
Anakinra Orphan exclusivity ends (one use only) Swedish Orphan BiovitrumIL1R1 0
Avacincaptad pegol sodium Patent ends AstellasC5 1
Bazedoxifene Patent ends PfizerESR1 0
Bevacizumab Orphan exclusivity ends (one use only) RocheVEGFA 2
Canakinumab Orphan exclusivity ends (one use only) NovartisIL1B 1

Companies with no follow-on: companies that market a drug at this target and have no successful follow-on of their own there (route B). Which companies they are is part of a plan.

All years, 2026 to 2035
Companies

Companies

Where each company has a drug that failed or went quiet (route A), or a marketed drug with no follow-on (route B).

CompanyABTargets
Pfizer84102336 targets
Novartis6387260 targets
GSK9058249 targets
AstraZeneca9451228 targets
Roche8637228 targets
Merck & Co.7343215 targets
Bristol Myers Squibb7239211 targets
All 2,274 companies
Targets

Targets

The protein a drug acts on, with the number of companies that need a new molecule for it, by route.

GeneUniProtAB
EGFRP005333015
PTGS2P35354628
KDRP35968258
PIK3CDO00329275
FLT3P36888256
HTR2AP28223922
All 1,259 targets
Drugs

Drugs

Every drug in the pipeline, past and present, with where it stands.

PaclitaxelMarketed
CisplatinMarketed
CarboplatinMarketed
GemcitabineMarketed
Of 17,976 drugs:
3,542marketed4,627active3,284stopped3,806went quiet207withdrawn from market2,510status not established
All 17,976 drugs
Therapeutic areas

Therapeutic areas

Targets grouped by the part of the body or the kind of disease they relate to.

Cancer437 targets
Immune system230 targets
Nervous system199 targets
Blood and lymph195 targets
Skin and connective tissue157 targets
Heart and blood vessels144 targets
Digestive system142 targets

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