US protection ending in 2032
As of the edition of 20 October 2026, 63 drugs have US protection that ends in 2032; 38 of them have at least one company on route B because of it.
Sources: FDA Orange Book and Purple Book, other approval registers.
63 drugs
| Drug | US protection | Status | Holder | Target | Route B rows |
|---|---|---|---|---|---|
| Ansuvimab | Ends 2032 (computed from the first US licence) | Marketed | Emergent Biosolutions | 0 | |
| Atoltivimab | Ends 2032 (computed from the first US licence) | Marketed | Regeneron | 0 | |
| Avatrombopag | Ends 2032 (exclusivity) | Marketed | Akarx | MPL | 2 |
| Avutometinib | Ends 2032 (exclusivity) | Marketed | Verastem | MAP2K1, MAP2K2 | 1 |
| Baricitinib | Ends 2032 (patent) | Marketed | Eli Lilly | JAK1, JAK2 | 4 |
| Belantamab mafodotin | Ends 2032 (computed from the first US licence) | Marketed | GSK | TNFRSF17, TUBB, TUBB1 | 8 |
| Bexagliflozin | Ends 2032 (patent) | Marketed | Theracosbio | SLC5A2 | 1 |
| Brexucabtagene autoleucel | Ends 2032 (computed from the first US licence) | Marketed | Gilead Sciences | CD19 | 0 |
| Cabozantinib | Ends 2032 (exclusivity) | Marketed | Exelixis | KDR | 2 |
| Capmatinib | Ends 2032 (patent) | Marketed | Novartis | MET | 1 |
| Cenobamate | Ends 2032 (patent) | Marketed | SK Life Science | SCN10A, SCN11A, SCN1A | 0 |
| Ceritinib | Ends 2032 (patent) | Marketed | Novartis | ALK | 1 |
| Cobicistat | Ends 2032 (patent) | Marketed | Gilead Sciences | 0 | |
| Copanlisib | Ends 2032 (patent) | Marketed | Bayer | PIK3CA, PIK3CD | 2 |
| Dacomitinib anhydrous | Ends 2032 (patent) | Marketed | Pfizer | EGFR | 1 |
| Dasabuvir | Ends 2032 (patent) | Marketed | AbbVie | 0 | |
| Defatted powder of arachis hypogaea l., semen (peanuts) | Ends 2032 (computed from the first US licence) | Marketed | Greer | 0 | |
| Difelikefalin | Ends 2032 (patent) | Marketed | CSL Behring | OPRK1 | 2 |
| Doravirine | Ends 2032 (patent) | Marketed | Merck & Co. | 0 | |
| Dordaviprone | Ends 2032 (exclusivity) | Marketed | Chimerix | CLPP, DRD2 | 2 |
| Duvelisib | Ends 2032 (patent) | Marketed | Secura Bio | PIK3CD, PIK3CG | 2 |
| Eculizumab | Ends 2032 (orphan exclusivity) | Marketed | AstraZeneca | C5 | 0 |
| Elamipretide | Ends 2032 (exclusivity) | Marketed | Stealth BioTherapeutics | 0 | |
| Emtricitabine | Ends 2032 (patent) | Marketed | Gilead Sciences | 0 | |
| Eptinezumab | Ends 2032 (computed from the first US licence) | Marketed | Lundbeck | CALCA, CALCB | 2 |
| Estradiol | Ends 2032 (patent) | Marketed | ESR1 | 6 | |
| Flortaucipir | Ends 2032 (patent) | Marketed | Avid Radiopharmaceuticals | MAPT | 2 |
| Fosnetupitant | Ends 2032 (patent) | Marketed | Helsinn Healthcare | TACR1 | 0 |
| Gilteritinib | Ends 2032 (patent) | Marketed | Astellas | AXL, FLT3 | 2 |
| Golimumab | Ends 2032 (orphan exclusivity) | Marketed | Johnson & Johnson | TNF | 0 |
| Inebilizumab | Ends 2032 (computed from the first US licence) | Marketed | Amgen | CD19 | 1 |
| Isatuximab | Ends 2032 (computed from the first US licence) | Marketed | Sanofi | CD38 | 1 |
| Leniolisib | Ends 2032 (patent) | Marketed | Pharming Technologies | PIK3CD | 1 |
| Lesinurad | Ends 2032 (patent) | Marketed | Ironwood Pharmaceuticals | SLC22A12 | 1 |
| Levomilnacipran | Ends 2032 (patent) | Marketed | AbbVie | SLC6A2 | 1 |
| Margetuximab | Ends 2032 (computed from the first US licence) | Marketed | MacroGenics | ERBB2 | 1 |
| Moxidectin | Ends 2032 (exclusivity) | Marketed | Medicines Development For Global Health | 0 | |
| Naloxegol | Ends 2032 (patent) | Marketed | Averitas Pharma | OPRM1 | 3 |
| Naxitamab | Ends 2032 (computed from the first US licence) | Marketed | Y-mAbs Therapeutics | 0 | |
| Neisseria meningitidis polysaccharide conjugated to tetanus toxoid | Ends 2032 (reference-product exclusivity) | Marketed | Sanofi | 0 | |
| Nerandomilast | Ends 2032 (exclusivity) | Marketed | Boehringer Ingelheim | PDE4B | 1 |
| Nilotinib | Ends 2032 (patent) | Marketed | Novartis | ABL1 | 0 |
| Odesivimab | Ends 2032 (computed from the first US licence) | Marketed | Regeneron | 0 | |
| Oliceridine | Ends 2032 (patent) | Marketed | Trevena | OPRM1 | 1 |
| Ombitasvir | Ends 2032 (patent) | Marketed | AbbVie | 0 | |
| Opicapone | Ends 2032 (patent) | Marketed | Amneal Pharmaceuticals | COMT | 2 |
| Osimertinib | Ends 2032 (patent) | Marketed | AstraZeneca | EGFR | 0 |
| Plazomicin | Ends 2032 (patent) | Marketed | Cipla | 0 | |
| Ponesimod | Ends 2032 (patent) | Marketed | Vanda Pharmaceuticals | S1PR1 | 2 |
| Regorafenib | Ends 2032 (patent) | Marketed | Bayer | BRAF, FGFR1, FGFR2 | 8 |
| Sacituzumab govitecan | Ends 2032 (computed from the first US licence) | Marketed | Gilead Sciences | TACSTD2, TOP1 | 2 |
| Satralizumab | Ends 2032 (computed from the first US licence) | Marketed | Roche | IL6R, IL6ST | 0 |
| Selumetinib | Ends 2032 (exclusivity) | Marketed | AstraZeneca | MAP2K1, MAP2K2 | 4 |
| Setmelanotide | Ends 2032 (patent) | Marketed | Rhythm Pharmaceuticals | MC4R | 1 |
| Somapacitan | Ends 2032 (computed from the first US licence) | Marketed | Novo Nordisk | GHR | 1 |
| Tafasitamab | Ends 2032 (computed from the first US licence) | Marketed | Incyte | CD19 | 1 |
| Tenofovir alafenamide | Ends 2032 (patent) | Marketed | Gilead Sciences | 0 | |
| Teprotumumab | Ends 2032 (computed from the first US licence) | Marketed | Amgen | IGF1R | 1 |
| Treosulfan | Ends 2032 (exclusivity) | Marketed | Medexus Pharma | 0 | |
| Venetoclax | Ends 2032 (patent) | Marketed | AbbVie | BCL2 | 1 |
| Vericiguat | Ends 2032 (patent) | Marketed | Merck & Co. | GUCY1A1, GUCY1A2, GUCY1B1 | 3 |
| Vonicog alfa | Ends 2032 (orphan exclusivity) | Marketed | Takeda | 0 | |
| Vonoprazan | Ends 2032 (exclusivity) | Marketed | Phathom Pharmaceuticals | ATP4A, ATP4B | 1 |
Listed by name. A route B row is one company at one target; for a drug with one target that is the number of companies. US protection is the US only, and it is not the date generics or biosimilars can enter.
Which companies are on route B in 2032
In the product38 of these 63 drugs have at least one company on route B. Which companies, and their scores, are in the product.
Get this list with the companies, scores and sources as a fileRequest access. Nothing is shown until you do.