Company

Madrigal Pharmaceuticals

As of the edition of 20 October 2026, Madrigal Pharmaceuticals runs 6 drugs, 1 of them marketed; it is on route A at 2 targets and on route B at 1 target.

Sources: ClinicalTrials.gov, FDA Orange Book and Purple Book, other approval registers, company records.

Family history

Madrigal Pharmaceuticals was renamed in 2016.

The records place 3 company names in this family.

  • Synta Pharmaceuticals Corp.: renamed in 2016

Drugs by status

StatusCount
Marketed1
Went quiet2
Stopped2
Status not established1
Total6

Marketed drugs and when their US protection ends

DrugUS protectionRoute B rows
ResmetiromEnds 2033 (patent)1

A route B row is one company at one target.

Where it needs a new molecule

Route A at 2 targets, route B at 1 target.

Three of its 3 rows, by target and route
TargetRoute
HSP90AB1 Heat shock protein HSP 90-betaRoute A
HSP90AA1 Heat shock protein HSP 90-alphaRoute A
THRB Thyroid hormone receptor betaRoute B

All 3 rows on route A or B

In the product

3 company-target rows on route A or B; 0 are not shown here, and no score is.

Where its trials are

  • Cancer: 18 trials led
  • Digestive system: 9 trials led
  • Blood and lymph: 4 trials led