Company

Merck KGaA

As of the edition of 20 October 2026, Merck KGaA runs 81 drugs, 23 of them marketed; it is on route A at 29 targets and on route B at 7 targets.

Sources: ClinicalTrials.gov, FDA Orange Book and Purple Book, other approval registers, company records.

Family history

The records place 8 company names in this family.

  • Springworks Therapeutics Inc: acquired in 2025; successor Merck KGaA, Darmstadt, Germany

Drugs by status

StatusCount
Marketed23
Active14
Went quiet11
Stopped29
Status not established4
Total81

Marketed drugs and when their US protection ends

DrugUS protectionRoute B rows
Metforminnone listed4
CetuximabEnded 2016 (computed from the first US licence)2
SomatropinEnded 2003 (orphan exclusivity)4
Mitoxantronenone listed1
AvelumabEnds 2029 (computed from the first US licence)1
Progesteronenone listed3
Levothyroxinenone listed6
Cladribinenone listed0
Follitropin alfaEnded 2009 (computed from the first US licence)0
Clomiphenenone listed1
Interferon beta-1aEnded 2008 (computed from the first US licence)0
Cetrorelixnone listed1
MenotropinsEnded 1987 (computed from the first US licence)2
Choriogonadotropin alfaEnded 2012 (computed from the first US licence)0
NirogacestatEnds 2039 (patent)1
TepotinibEnds 2030 (patent)1
MirdametinibEnds 2041 (patent)2
Lutropin alfanone listed0
AtaciceptEnds 2038 (computed from the first US licence)2
Hydroxocobalaminnone listed0
Cobalaminnone listed0
Praziquantel, (r)-none listed0
Sermorelin acetatenone listed1

A route B row is one company at one target.

Where it needs a new molecule

Route A at 29 targets, route B at 7 targets.

Three of its 36 rows, by target and route
TargetRoute
ITGAV Integrin alpha-VRoute A
GHRHR Growth hormone-releasing hormone receptorRoute B
RAF1 RAF proto-oncogene serine/threonine-protein kinaseRoute A

All 36 rows on route A or B

In the product

36 company-target rows on route A or B; 33 are not shown here, and no score is.

Where its trials are

  • Cancer: 113 trials led
  • Lungs and airways: 39 trials led
  • Urinary and reproductive: 34 trials led