Abrocitinib
As of the edition of 20 October 2026, Abrocitinib is a small molecule: marketed, first approved in 2021 (JP); acts on JAK1; US protection ends in 2036.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2022
- Kind
- Small molecule
- Brand name
- Cibinqo
- First approved
- 27 September 2021 (JP)
- Approvals on record
- 10 in 5 regions
- Holder of the most recent approval
- Pfizer; 2 holders in all
- Registered trials
- 51, 1 stopped early
- Disease areas
- Skin and connective tissue; Immune system; Inherited and neonatal; Blood and lymph; Cancer; Nutrition and metabolism
US protection
US protection ends in 2036.
The last listed US drug-substance patent ends in 2036. The application that gives this date is held by Pfizer.
This is the US only, and it is not the date generics or biosimilars can enter.
The exact date and the listings behind it
In the product12 listings count towards this date. The exact date and each listing are in the product.
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Target
| Gene | Protein | UniProt |
|---|---|---|
| JAK1 | Tyrosine-protein kinase JAK1 | P23458 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 10 | 0 | 8 | 0 |
| Phase 1 | 18 | 17 | 1 | 0 |
| Phase 2 | 10 | 5 | 4 | 1 |
| Phase 3 | 11 | 8 | 3 | 0 |
| Phase 4 | 2 | 1 | 1 | 0 |
| All trials | 51 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Pfizer | Applicant and Lead sponsor of trials | 2021 to now |