Drug

Acadesine

As of the edition of 20 October 2026, Acadesine is a small molecule: stopped in 2015; acts on PRKAA1 and PRKAA2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2015
Kind
Small molecule
Registered trials
2, 1 stopped early
Disease areas
Blood and lymph; Cancer; Immune system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Acadesine.

Targets

GeneProteinUniProt
PRKAA25'-AMP-activated protein kinase catalytic subunit alpha-2P54646
PRKAA15'-AMP-activated protein kinase catalytic subunit alpha-1Q13131

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 22101
All trials2

Who ran its trials

CompanyRoleYears
Advancell - Advanced In Vitro CellLead sponsor of trials2007 to now