Drug

Adriforant

As of the edition of 20 October 2026, Adriforant is a small molecule: stopped in 2020; acts on HRH4.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2020
Kind
Small molecule
Registered trials
6, 2 stopped early
Disease areas
Immune system; Skin and connective tissue; Inherited and neonatal; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 companies on route A because of this drug.

Companies on route A for this drug

In the product

3 companies are on route A because of Adriforant.

Target

GeneProteinUniProt
HRH4Histamine H4 receptorQ9H3N8

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 24202
All trials6

Who ran its trials

CompanyRoleYears
PfizerLead sponsor of trials2009 to now
Ziarco PharmaLead sponsor of trials2015 to now
NovartisLead sponsor of trials2018 to now