Drug

Afimoxifene

As of the edition of 20 October 2026, Afimoxifene is a small molecule: stopped in 2024; acts on ESR1, ESR2 and ESRRG.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2024
Kind
Small molecule
Registered trials
7, 2 stopped early
Disease areas
Cancer; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of Afimoxifene.

Targets

GeneProteinUniProt
ESR1Estrogen receptorP03372
ESRRGEstrogen-related receptor gammaP62508
ESR2Estrogen receptor betaQ92731

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1100
Phase 25311
Phase 31001
All trials7

Who ran its trials

CompanyRoleYears
BHR PharmaLead sponsor of trials2017 to now