Drug

Alfimeprase

As of the edition of 20 October 2026, Alfimeprase is an enzyme: stopped in 2008; acts on FGA, FGB and FGG.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2008
Kind
Enzyme
Registered trials
7, 2 stopped early
Disease areas
Heart and blood vessels; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
FGAFibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]P02671
FGBFibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]P02675
FGGFibrinogen gamma chainP02679

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 23201
Phase 34301
All trials7

Who ran its trials

CompanyRoleYears
Oruka TherapeuticsLead sponsor of trials2003 to now