Drug

Amiselimod

As of the edition of 20 October 2026, Amiselimod is a small molecule: in active development; acts on S1PR1, S1PR2 and S1PR3 and 2 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2015
Kind
Small molecule
Registered trials
11, 0 stopped early
Disease areas
Digestive system; Immune system; Nervous system; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
S1PR2Sphingosine 1-phosphate receptor 2O95136
S1PR4Sphingosine 1-phosphate receptor 4O95977
S1PR1Sphingosine 1-phosphate receptor 1P21453
S1PR3Sphingosine 1-phosphate receptor 3Q99500
S1PR5Sphingosine 1-phosphate receptor 5Q9H228

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 15500
Phase 26600
All trials11

Who ran its trials

CompanyRoleYears
Tanabe PharmaLead sponsor of trials2014 to now
Bausch HealthLead sponsor of trials2021 to now