Drug

Arbaclofen placarbil

As of the edition of 20 October 2026, Arbaclofen placarbil is a small molecule: went quiet in 2017; acts on GABBR1 and GABBR2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2017
Kind
Small molecule
Registered trials
6, 0 stopped early
Disease areas
Digestive system; Chemically induced; Mental health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Arbaclofen placarbil.

Targets

GeneProteinUniProt
GABBR2Gamma-aminobutyric acid type B receptor subunit 2O75899
GABBR1Gamma-aminobutyric acid type B receptor subunit 1Q9UBS5

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 25500
All trials6

Who ran its trials

CompanyRoleYears
IndiviorLead sponsor of trials2005 to now
Arbor PharmaceuticalsLead sponsor of trials2007 to now