Drug

Arq-736 free acid

As of the edition of 20 October 2026, Arq-736 free acid is a small molecule: went quiet in 2013; acts on BRAF and RAF1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2013
Kind
Small molecule
Registered trials
1, 0 stopped early

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Arq-736 free acid.

Targets

GeneProteinUniProt
RAF1RAF proto-oncogene serine/threonine-protein kinaseP04049
BRAFSerine/threonine-protein kinase B-rafP15056

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
All trials1

Who ran its trials

CompanyRoleYears
Merck & Co.Lead sponsor of trials2010 to now