Drug

Arzoxifene

As of the edition of 20 October 2026, Arzoxifene is a small molecule: went quiet in 2009; acts on ESR1 and ESR2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2009
Kind
Small molecule
Registered trials
12, 0 stopped early
Disease areas
Cancer; Skin and connective tissue; Bones, joints and muscles; Nutrition and metabolism; Pregnancy and women's health; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
ESR1Estrogen receptorP03372
ESR2Estrogen receptor betaQ92731

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 26600
Phase 34400
Phase 41100
All trials12

Who ran its trials

CompanyRoleYears
Eli LillyLead sponsor of trials2001 to now