Avadomide
As of the edition of 20 October 2026, Avadomide is a small molecule: in active development; acts on CRBN.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Active, 2026
- Kind
- Small molecule
- Registered trials
- 15, 3 stopped early
- Disease areas
- Cancer; Blood and lymph; Immune system; Digestive system; Heart and blood vessels; Pregnancy and women's health
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Target
| Gene | Protein | UniProt |
|---|---|---|
| CRBN | Protein cereblon | Q96SW2 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 11 | 7 | 1 | 3 |
| Phase 2 | 4 | 4 | 0 | 0 |
| All trials | 15 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| Bristol Myers Squibb | Lead sponsor of trials | 2011 to now |