Drug

AZD-2927

As of the edition of 20 October 2026, AZD-2927 is a small molecule: went quiet in 2012; acts on KCNJ3 and KCNJ5.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2012
Kind
Small molecule
Registered trials
2, 0 stopped early
Disease areas
Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of AZD-2927.

Targets

GeneProteinUniProt
KCNJ5G protein-activated inward rectifier potassium channel 4P48544
KCNJ3G protein-activated inward rectifier potassium channel 1P48549

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 21100
All trials2

Who ran its trials

CompanyRoleYears
AstraZenecaLead sponsor of trials2011 to now