Drug

AZD-8186

As of the edition of 20 October 2026, AZD-8186 is a small molecule: of no established status; acts on PIK3CB and PIK3CD.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Status not established
Kind
Small molecule
Registered trials
3, 0 stopped early
Disease areas
Cancer; Skin and connective tissue; Digestive system; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformO00329
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformP42338

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 21000
All trials3

Who ran its trials

CompanyRoleYears
AstraZenecaLead sponsor of trials2013 to now