Drug

AZD-8848

As of the edition of 20 October 2026, AZD-8848 is a small molecule: went quiet in 2014; acts on TLR7.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2014
Kind
Small molecule
Registered trials
10, 0 stopped early
Disease areas
Lungs and airways; Ear, nose and throat; Immune system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 companies on route A because of this drug.

Companies on route A for this drug

In the product

2 companies are on route A because of AZD-8848.

Target

GeneProteinUniProt
TLR7Toll-like receptor 7Q9NYK1

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1100
Phase 17700
Phase 22200
All trials10

Who ran its trials

CompanyRoleYears
AstraZenecaLead sponsor of trials2008 to now
Sumitomo PharmaLead sponsor of trials2009 to now