Calcium
As of the edition of 20 October 2026, Calcium is a small molecule: marketed, first approved in 1934 (CH).
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2025
- Kind
- Small molecule
- Brand name
- Lactated Ringer's In Plastic Container
- First approved
- 31 August 1934 (CH)
- Approvals on record
- 230 in 5 regions
- Holder of the most recent approval
- Clinigen; 24 holders in all
- Registered trials
- 84, 5 stopped early
- Disease areas
- Bones, joints and muscles; Nutrition and metabolism; Cancer; Urinary and reproductive; Skin and connective tissue; Hormones
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 14 | 7 | 2 | 1 |
| Phase 1 | 4 | 4 | 0 | 0 |
| Phase 2 | 22 | 13 | 2 | 3 |
| Phase 3 | 28 | 23 | 1 | 1 |
| Phase 4 | 16 | 12 | 2 | 0 |
| All trials | 84 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Baxter Healthcare | Applicant | 1957 to now |
| B. Braun Medical | Applicant | 1974 to now |
| Alcon | Later holder | 1980 to now |
| Pfizer | Acquired holder and Later holder | 1981 to now |
| Bayer | Later holder | 1984 to now |
| Braintree | Applicant | 1990 to now |
| Johnson & Johnson | Later holder | 1994 to now |
| Abbott | Later holder | 2000 to now |
| Fresenius Medical Care | Later holder | 2011 to now |
| Fresenius Kabi | Later holder | 2017 to now |
| Hq Specialty Pharma | Later holder | 2018 to now |
| Fresenius Medical Care Renal Therapies | Acquired holder | 2025 to now |
| Clinigen | Applicant | 2025 to now |