Calcium carbonate
As of the edition of 20 October 2026, Calcium carbonate is a small molecule: marketed, first approved in 1936 (CH).
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2000
- Kind
- Small molecule
- Brand name
- Pepcid Complete
- First approved
- 8 June 1936 (CH)
- Approvals on record
- 13 in 4 regions
- Holder of the most recent approval
- Bayer; 6 holders in all
- Registered trials
- 63, 7 stopped early
- Disease areas
- Nutrition and metabolism; Bones, joints and muscles; Cancer; Urinary and reproductive; Immune system; Pregnancy and women's health
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 7 | 6 | 0 | 1 |
| Phase 1 | 15 | 14 | 0 | 1 |
| Phase 2 | 20 | 19 | 0 | 1 |
| Phase 3 | 16 | 12 | 0 | 4 |
| Phase 4 | 5 | 3 | 1 | 0 |
| All trials | 63 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Bayer | Applicant and Lead sponsor of trials | 1936 to now |
| Reckitt Benckiser | Later holder | 2013 to now |