CDX-1140
As of the edition of 20 October 2026, CDX-1140 is a drug: in active development; acts on CD40.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Active, 2024
- Kind
- Unknown
- Registered trials
- 12, 3 stopped early
- Disease areas
- Cancer; Skin and connective tissue; Digestive system; Hormones; Lungs and airways; Ear, nose and throat
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Companies that need a new molecule because of this drug
1 company on route A because of this drug.
Companies on route A for this drug
In the product1 company is on route A because of CDX-1140.
See the 1 company on route A for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| CD40 | Tumor necrosis factor receptor superfamily member 5 | P25942 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 6 | 1 | 4 | 1 |
| Phase 2 | 6 | 1 | 3 | 2 |
| All trials | 12 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| Celldex Therapeutics | Lead sponsor of trials | 2017 to now |
| HiberCell | Lead sponsor of trials | 2022 to now |