Drug

Chlorprothixene

As of the edition of 20 October 2026, Chlorprothixene is a small molecule: marketed, first approved in 1982 (US); acts on DRD2, DRD3 and HTR2A and 1 more; no US protection is listed.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1982
Kind
Small molecule
Brand name
Taractan
First approved
1 January 1982 (US)
Approvals on record
6 in 1 region
Holder of the most recent approval
Roche
Registered trials
2, 1 stopped early
Disease areas
Mental health; Nervous system; Nutrition and metabolism

US protection

No US protection is listed.

The FDA registers list no drug-substance patent or exclusivity that counts for this drug.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route B because of this drug.

Companies on route B for this drug

In the product

1 company-target row is on route B because of Chlorprothixene.

Targets

GeneProteinUniProt
DRD2Dopamine receptor D2P14416
HTR2A5-hydroxytryptamine receptor 2AP28223
HTR2C5-hydroxytryptamine receptor 2CP28335
DRD3Dopamine receptor D3P35462

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1010
Phase 31001
All trials2

Who has held its approvals

CompanyRoleYears
RocheLater holder and Earlier holder