Drug

Crenolanib

As of the edition of 20 October 2026, Crenolanib is a small molecule: stopped in 2020; acts on FLT3, PDGFRA and PDGFRB.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2020
Kind
Small molecule
Registered trials
20, 4 stopped early
Disease areas
Cancer; Blood and lymph; Nervous system; Digestive system; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of Crenolanib.

Targets

GeneProteinUniProt
PDGFRBPlatelet-derived growth factor receptor betaP09619
PDGFRAPlatelet-derived growth factor receptor alphaP16234
FLT3Receptor-type tyrosine-protein kinase FLT3P36888

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1000
Phase 14400
Phase 211803
Phase 34201
All trials20

Who ran its trials

CompanyRoleYears
Arog PharmaceuticalsLead sponsor of trials