Drug

Danicamtiv

As of the edition of 20 October 2026, Danicamtiv is a small molecule: in active development; acts on MYH6, MYH7 and MYH7B and 4 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2026
Kind
Small molecule
Registered trials
9, 1 stopped early
Disease areas
Heart and blood vessels; Inherited and neonatal; Bones, joints and muscles; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
MYH7BMyosin-7BA7E2Y1
MYL3Myosin light chain 3P08590
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoformP10916
MYL4Myosin light chain 4P12829
MYH7Myosin-7P12883
MYH6Myosin-6P13533
MYL7Myosin regulatory light chain 2, atrial isoformQ01449

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 15500
Phase 22101
Phase 32020
All trials9

Who ran its trials

CompanyRoleYears
Bristol Myers SquibbLead sponsor of trials2017 to now
KardiganLead sponsor of trials2026 to now