Daprodustat
As of the edition of 20 October 2026, Daprodustat is a small molecule: marketed, first approved in 2020 (JP); acts on EGLN1, EGLN2 and EGLN3 and 1 more; US protection ends in 2038.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2023
- Kind
- Small molecule
- Brand name
- Jesduvroq
- First approved
- 29 June 2020 (JP)
- Approvals on record
- 7 in 2 regions
- Holder of the most recent approval
- GSK; 2 holders in all
- Registered trials
- 40, 3 stopped early
- Disease areas
- Blood and lymph; Pregnancy and women's health; Urinary and reproductive; Heart and blood vessels; Bones, joints and muscles; Hormones
US protection
US protection ends in 2038.
The last listed US drug-substance patent ends in 2038. The application that gives this date is held by GSK.
This is the US only, and it is not the date generics or biosimilars can enter.
The exact date and the listings behind it
In the product20 listings count towards this date. The exact date and each listing are in the product.
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Companies that need a new molecule because of this drug
4 company-target rows on route B because of this drug.
Companies on route B for this drug
In the product4 company-target rows are on route B because of Daprodustat.
See the 4 company-target rows on route B for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Targets
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 1 | 0 | 1 | 0 |
| Phase 1 | 17 | 16 | 0 | 1 |
| Phase 2 | 12 | 10 | 0 | 2 |
| Phase 3 | 9 | 8 | 1 | 0 |
| Phase 4 | 1 | 1 | 0 | 0 |
| All trials | 40 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| GSK | Applicant and Lead sponsor of trials | 2008 to now |