Drug

Darotropium

As of the edition of 20 October 2026, Darotropium is a small molecule: went quiet in 2009; acts on CHRM1, CHRM2 and CHRM3 and 2 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2009
Kind
Small molecule
Registered trials
11, 0 stopped early
Disease areas
Lungs and airways; Infections

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route B and 3 company-target rows on route A because of this drug.

Companies on route B for this drug

In the product

1 company-target row is on route B because of Darotropium.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of Darotropium.

Targets

GeneProteinUniProt
CHRM2Muscarinic acetylcholine receptor M2P08172
CHRM4Muscarinic acetylcholine receptor M4P08173
CHRM5Muscarinic acetylcholine receptor M5P08912
CHRM1Muscarinic acetylcholine receptor M1P11229
CHRM3Muscarinic acetylcholine receptor M3P20309

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 16600
Phase 25500
All trials11

Who ran its trials

CompanyRoleYears
GSKLead sponsor of trials2005 to now