Drug

Dulanermin

As of the edition of 20 October 2026, Dulanermin is a protein: went quiet in 2018; acts on TNFRSF10A and TNFRSF10B.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2018
Kind
Protein
Registered trials
5, 1 stopped early
Disease areas
Cancer; Digestive system; Lungs and airways; Blood and lymph; Immune system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

6 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

6 company-target rows are on route A because of Dulanermin.

Targets

GeneProteinUniProt
TNFRSF10ATumor necrosis factor receptor superfamily member 10AO00220
TNFRSF10BTumor necrosis factor receptor superfamily member 10BO14763

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 22101
Phase 31000
All trials5

Who ran its trials

CompanyRoleYears
AmgenLead sponsor of trials2006 to now
RocheLead sponsor of trials2006 to now
Gebaide BiotechnologyLead sponsor of trials2016 to now