Drug

E-7016

As of the edition of 20 October 2026, E-7016 is a small molecule: stopped in 2014; acts on PARP1, PARP2 and PARP3.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2014
Kind
Small molecule
Registered trials
1, 1 stopped early

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route A because of this drug.

Companies on route A for this drug

In the product

1 company-target row is on route A because of E-7016.

Targets

GeneProteinUniProt
PARP1Poly [ADP-ribose] polymerase 1P09874
PARP2Poly [ADP-ribose] polymerase 2Q9UGN5
PARP3Protein mono-ADP-ribosyltransferase PARP3Q9Y6F1

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 21001
All trials1

Who ran its trials

CompanyRoleYears
EisaiLead sponsor of trials2012 to now