Drug

Edasalonexent

As of the edition of 20 October 2026, Edasalonexent is a small molecule: stopped in 2020; acts on NFKB1, NFKB2 and RELA.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2020
Kind
Small molecule
Registered trials
6, 1 stopped early
Disease areas
Bones, joints and muscles; Inherited and neonatal; Nervous system; Hormones; Nutrition and metabolism

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
NFKB1Nuclear factor NF-kappa-B p105 subunitP19838
NFKB2Nuclear factor NF-kappa-B p100 subunitQ00653
RELATranscription factor p65Q04206

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13300
Phase 21100
Phase 32101
All trials6

Who ran its trials

CompanyRoleYears
BioCryst PharmaceuticalsLead sponsor of trials2011 to now