Probatebeta
Drug

EFB0027

As of the edition of 20 October 2026, EFB0027 is a drug known only by a code name: went quiet in 2012; acts on COXFA4, COXFA4L2 and GPD2 and 47 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2012
Kind
Code name only
Registered trials
1, 0 stopped early
Disease areas
Hormones; Nutrition and metabolism

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

50 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

50 company-target rows are on route A because of EFB0027.

See the 50 company-target rows on route A for this drug, with the facts behind eachRequest access. Nothing is shown until you do.

Targets

GeneProteinUniProt
NDUFS8NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrialO00217
COXFA4Cytochrome c oxidase subunit FA4O00483
NDUFAB1Acyl carrier protein, mitochondrialO14561
NDUFA1NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1O15239
NDUFS4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrialO43181
NDUFB5NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrialO43674
NDUFB3NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3O43676
NDUFC1NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrialO43677
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2O43678
NDUFS5NADH dehydrogenase [ubiquinone] iron-sulfur protein 5O43920
NDUFS7NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialO75251
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialO75306
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrialO75380
NDUFB1NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1O75438
NDUFS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialO75489
NDUFB6NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6O95139
NDUFA3NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3O95167
NDUFB4NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4O95168
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrialO95169
NDUFB2NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrialO95178
NDUFA7NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7O95182
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2O95298
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrialO95299
NDUFB10NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10O96000
MT-ND1NADH-ubiquinone oxidoreductase chain 1P03886
MT-ND2NADH-ubiquinone oxidoreductase chain 2P03891
MT-ND3NADH-ubiquinone oxidoreductase chain 3P03897
MT-ND4LNADH-ubiquinone oxidoreductase chain 4LP03901
MT-ND5NADH-ubiquinone oxidoreductase chain 5P03915
MT-ND6NADH-ubiquinone oxidoreductase chain 6P03923
NDUFB7NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7P17568
NDUFV2NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrialP19404
NDUFS1NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrialP28331
GPD2Glycerol-3-phosphate dehydrogenase, mitochondrialP43304
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrialP49821
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8P51970
NDUFV3NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrialP56181
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6P56556
NDUFA5NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5Q16718
NDUFA9NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrialQ16795
NDUFA11NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11Q86Y39
NDUFAF2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2Q8N183
NDUFAF3NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3Q9BU61
COXFA4L2Cytochrome c oxidase hypoxia associated subunit FA4L2Q9NRX3
NDUFB11NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrialQ9NX14
NDUFAF4NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4Q9P032
NDUFA13NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13Q9P0J0
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12Q9UI09
NDUFAF1Complex I intermediate-associated protein 30, mitochondrialQ9Y375
NDUFB9NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9Q9Y6M9

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 21100
All trials1

Who ran its trials

CompanyRoleYears
Elcelyx TherapeuticsLead sponsor of trials2012 to now