Drug

ES101

As of the edition of 20 October 2026, ES101 is a drug known only by a code name: stopped in 2024; acts on CD274 and TNFRSF9.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2024
Kind
Code name only
Registered trials
2, 2 stopped early
Disease areas
Cancer; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of ES101.

Targets

GeneProteinUniProt
TNFRSF9Tumor necrosis factor receptor superfamily member 9Q07011
CD274Programmed cell death 1 ligand 1Q9NZQ7

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11001
Phase 21001
All trials2

Who ran its trials

CompanyRoleYears
Elpiscience BiopharmaLead sponsor of trials2019 to now