Drug

Fexagratinib

As of the edition of 20 October 2026, Fexagratinib is a small molecule: in active development; acts on FGFR1, FGFR2 and FGFR3 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2015
Kind
Small molecule
Registered trials
19, 2 stopped early
Disease areas
Cancer; Skin and connective tissue; Digestive system; Lungs and airways; Blood and lymph; Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Fexagratinib.

Targets

GeneProteinUniProt
FGFR1Fibroblast growth factor receptor 1P11362
FGFR2Fibroblast growth factor receptor 2P21802
FGFR4Fibroblast growth factor receptor 4P22455
FGFR3Fibroblast growth factor receptor 3P22607

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1100
Phase 14211
Phase 213721
Phase 31100
All trials19

Who ran its trials

CompanyRoleYears
AstraZenecaLead sponsor of trials2009 to now
Abbisko TherapeuticsLead sponsor of trials2020 to now