Drug

Flotetuzumab

As of the edition of 20 October 2026, Flotetuzumab is an antibody: stopped in 2024; acts on CD3D, CD3E and CD3G and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2024
Kind
Antibody
Registered trials
8, 4 stopped early
Disease areas
Blood and lymph; Cancer; Immune system; Skin and connective tissue; Infections

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
CD3DT-cell surface glycoprotein CD3 delta chainP04234
CD3ET-cell surface glycoprotein CD3 epsilon chainP07766
CD3GT-cell surface glycoprotein CD3 gamma chainP09693
IL3RAInterleukin-3 receptor subunit alphaP26951

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1000
Phase 13210
Phase 24004
All trials8

Who ran its trials

CompanyRoleYears
MacroGenicsLead sponsor of trials