GFH312
As of the edition of 20 October 2026, GFH312 is a drug known only by a code name: stopped in 2024; acts on RIPK1.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Stopped, 2024
- Kind
- Code name only
- Registered trials
- 3, 1 stopped early
- Disease areas
- Heart and blood vessels
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Target
| Gene | Protein | UniProt |
|---|---|---|
| RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | Q13546 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 2 | 2 | 0 | 0 |
| Phase 2 | 1 | 0 | 0 | 1 |
| All trials | 3 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| GenFleet Therapeutics | Lead sponsor of trials | 2021 to now |
| Zhejiang Genfleet Therapeutics | Lead sponsor of trials | 2022 to now |