Drug

HT-0712

As of the edition of 20 October 2026, HT-0712 is a small molecule: went quiet in 2015; acts on PDE4A, PDE4B and PDE4C and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2015
Kind
Small molecule
Registered trials
3, 1 stopped early
Disease areas
Ear, nose and throat; Immune system; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of HT-0712.

Targets

GeneProteinUniProt
PDE4A3',5'-cyclic-AMP phosphodiesterase 4AP27815
PDE4B3',5'-cyclic-AMP phosphodiesterase 4BQ07343
PDE4C3',5'-cyclic-AMP phosphodiesterase 4CQ08493
PDE4D3',5'-cyclic-AMP phosphodiesterase 4DQ08499

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11001
Phase 22200
All trials3

Who ran its trials

CompanyRoleYears
Dart NeuroScienceLead sponsor of trials2008 to now