Drug

Izencitinib

As of the edition of 20 October 2026, Izencitinib is a small molecule: stopped in 2021; acts on JAK1, JAK2 and JAK3 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2021
Kind
Small molecule
Registered trials
8, 2 stopped early
Disease areas
Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
JAK2Tyrosine-protein kinase JAK2O60674
JAK1Tyrosine-protein kinase JAK1P23458
TYK2Non-receptor tyrosine-protein kinase TYK2P29597
JAK3Tyrosine-protein kinase JAK3P52333

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 16600
Phase 32002
All trials8

Who ran its trials

CompanyRoleYears
Theravance BiopharmaLead sponsor of trials2015 to now