Drug

K-134

As of the edition of 20 October 2026, K-134 is a small molecule: went quiet in 2010; acts on PDE3A and PDE3B.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2010
Kind
Small molecule
Registered trials
1, 0 stopped early
Disease areas
Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of K-134.

Targets

GeneProteinUniProt
PDE3BcGMP-inhibited 3',5'-cyclic phosphodiesterase 3BQ13370
PDE3AcGMP-inhibited 3',5'-cyclic phosphodiesterase 3AQ14432

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 21100
All trials1

Who ran its trials

CompanyRoleYears
KowaLead sponsor of trials2008 to now