Drug

Labetuzumab govitecan

As of the edition of 20 October 2026, Labetuzumab govitecan is an antibody drug conjugate: stopped in 2017; acts on CEACAM5 and TOP1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2017
Kind
Antibody drug conjugate
Registered trials
3, 2 stopped early
Disease areas
Cancer; Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route B and 1 company-target row on route A because of this drug.

Companies on route B for this drug

In the product

1 company-target row is on route B because of Labetuzumab govitecan.

Companies on route A for this drug

In the product

1 company-target row is on route A because of Labetuzumab govitecan.

Targets

GeneProteinUniProt
CEACAM5Cell adhesion molecule CEACAM5P06731
TOP1DNA topoisomerase 1P11387

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 22002
All trials3

Who ran its trials

CompanyRoleYears
Gilead SciencesLead sponsor of trials2011 to now