Drug

LCZ 696

As of the edition of 20 October 2026, LCZ 696 is a drug known only by a code name: stopped in 2014; acts on AGTR1 and MME.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2014
Kind
Code name only
Registered trials
5, 1 stopped early
Disease areas
Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

2 company-target rows are on route B because of LCZ 696.

Targets

GeneProteinUniProt
MMENeprilysinP08473
AGTR1Type-1 angiotensin II receptorP30556

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1100
Phase 21100
Phase 31001
Phase 42200
All trials5

Who ran its trials

CompanyRoleYears
NovartisLead sponsor of trials2009 to now