Drug

Lestaurtinib

As of the edition of 20 October 2026, Lestaurtinib is a small molecule: in active development; acts on FLT3, JAK2 and RET.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2008
Kind
Small molecule
Registered trials
10, 1 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Inherited and neonatal; Skin and connective tissue; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of Lestaurtinib.

Targets

GeneProteinUniProt
JAK2Tyrosine-protein kinase JAK2O60674
RETProto-oncogene tyrosine-protein kinase receptor RetP07949
FLT3Receptor-type tyrosine-protein kinase FLT3P36888

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 28601
Phase 31100
All trials10

Who ran its trials

CompanyRoleYears
TevaLead sponsor of trials2002 to now