Drug

Levomepromazine

As of the edition of 20 October 2026, Levomepromazine is a small molecule: marketed, first approved in 1958 (CH); acts on DRD2, DRD3 and DRD4.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1988
Kind
Small molecule
Brand name
Levoprome
First approved
18 February 1958 (CH)
Approvals on record
5 in 5 regions
Holder of the most recent approval
NEURAXPHARM FRANCE; 5 holders in all
Registered trials
1, 1 stopped early
Disease areas
Mental health; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
DRD2Dopamine receptor D2P14416
DRD4Dopamine receptor D4P21917
DRD3Dopamine receptor D3P35462

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 31001
All trials1

Who has held its approvals

CompanyRoleYears
AmgenAcquired holder2003 to now
PfizerEarlier holder