Drug

LY-2780301

As of the edition of 20 October 2026, LY-2780301 is a drug: stopped in 2018; acts on AKT1, AKT2 and AKT3 and 2 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2018
Kind
Unknown
Registered trials
3, 1 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of LY-2780301.

Targets

GeneProteinUniProt
RPS6KB1Ribosomal protein S6 kinase beta-1P23443
AKT1RAC-alpha serine/threonine-protein kinaseP31749
AKT2RAC-beta serine/threonine-protein kinaseP31751
RPS6KB2Ribosomal protein S6 kinase beta-2Q9UBS0
AKT3RAC-gamma serine/threonine-protein kinaseQ9Y243

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 21001
All trials3

Who ran its trials

CompanyRoleYears
Eli LillyLead sponsor of trials2010 to now