Drug

Mavrilimumab

As of the edition of 20 October 2026, Mavrilimumab is an antibody: went quiet in 2020; acts on CSF2RA and CSF2RB.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2020
Kind
Antibody
Registered trials
7, 1 stopped early
Disease areas
Bones, joints and muscles; Immune system; Skin and connective tissue; Infections; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route A because of this drug.

Companies on route A for this drug

In the product

1 company-target row is on route A because of Mavrilimumab.

Targets

GeneProteinUniProt
CSF2RAGranulocyte-macrophage colony-stimulating factor receptor subunit alphaP15509
CSF2RBCytokine receptor common subunit betaP32927

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 26401
All trials7

Who ran its trials

CompanyRoleYears
AstraZenecaLead sponsor of trials2010 to now