Drug

MK-8777

As of the edition of 20 October 2026, MK-8777 is a drug: went quiet in 2009; acts on GRIA1, GRIA2 and GRIA3 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2009
Kind
Unknown
Registered trials
2, 0 stopped early
Disease areas
Mental health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of MK-8777.

Targets

GeneProteinUniProt
GRIA1Glutamate receptor 1P42261
GRIA2Glutamate receptor 2P42262
GRIA3Glutamate receptor 3P42263
GRIA4Glutamate receptor 4P48058

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 22200
All trials2

Who ran its trials

CompanyRoleYears
Merck & Co.Lead sponsor of trials2007 to now