Mometasone furoate
As of the edition of 20 October 2026, Mometasone furoate is a small molecule: marketed, first approved in 1987 (US); acts on NR3C1; no US protection of its own is listed.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2020
- Kind
- Small molecule
- Brand name
- Elocon
- First approved
- 30 April 1987 (US)
- Approvals on record
- 28 in 5 regions
- Holder of the most recent approval
- Perrigo Pharma International Dac; 9 holders in all
- Registered trials
- 126, 11 stopped early
- Disease areas
- Lungs and airways; Immune system; Ear, nose and throat; Skin and connective tissue; Infections; Nervous system
US protection
No US protection of its own is listed.
The FDA registers list no drug-substance patent or exclusivity of its own that counts for this drug.
Glenmark Specialty holds a later exclusivity on its own new formulation or combination product, ending 2039; it does not protect the original drug.
This is the US only.
Companies that need a new molecule because of this drug
3 companies on route B because of this drug.
Companies on route B for this drug
In the product3 companies are on route B because of Mometasone furoate.
See the 3 companies on route B for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| NR3C1 | Glucocorticoid receptor | P04150 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 8 | 3 | 5 | 0 |
| Phase 1 | 5 | 3 | 0 | 1 |
| Phase 2 | 31 | 26 | 1 | 3 |
| Phase 3 | 54 | 50 | 2 | 1 |
| Phase 4 | 28 | 16 | 2 | 6 |
| All trials | 126 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Merck & Co. | Earlier holder | 1987 to now |
| Organon | Acquired holder and Lead sponsor of trials | 1993 to now |
| Novartis | Applicant and Lead sponsor of trials | 2006 to now |
| Medtronic | Later holder and Lead sponsor of trials | 2013 to now |
| Perrigo Pharma International Dac | Later holder | 2022 to now |