Motugivatrep
As of the edition of 20 October 2026, Motugivatrep is a small molecule: marketed, first approved in 2025 (JP); acts on TRPV1.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2025
- Kind
- Small molecule
- Brand name
- Avarept
- First approved
- 22 December 2025 (JP)
- Approvals on record
- 2 in 1 region
- Holder of the most recent approval
- Senju Pharmaceutical
- Registered trials
- 2, 0 stopped early
- Disease areas
- Eye
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Companies that need a new molecule because of this drug
1 company on route B because of this drug.
Companies on route B for this drug
In the product1 company is on route B because of Motugivatrep.
See the 1 company on route B for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| TRPV1 | Transient receptor potential cation channel subfamily V member 1 | Q8NER1 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 2 | 1 | 1 | 0 | 0 |
| Phase 3 | 1 | 1 | 0 | 0 |
| All trials | 2 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Senju Pharmaceutical | Originator and Lead sponsor of trials | 2019 to now |