Drug

Nanatinostat

As of the edition of 20 October 2026, Nanatinostat is a small molecule: stopped in 2025; acts on HDAC1, HDAC2 and HDAC3.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2025
Kind
Small molecule
Registered trials
4, 3 stopped early
Disease areas
Cancer; Digestive system; Ear, nose and throat; Infections; Mouth and teeth

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of Nanatinostat.

Targets

GeneProteinUniProt
HDAC3Histone deacetylase 3O15379
HDAC1Histone deacetylase 1Q13547
HDAC2Histone deacetylase 2Q92769

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13102
Phase 21001
All trials4

Who ran its trials

CompanyRoleYears
Chroma TherapeuticsLead sponsor of trials2008 to now
Viracta TherapeuticsLead sponsor of trials2021 to now