Drug

Navicixizumab

As of the edition of 20 October 2026, Navicixizumab is an antibody: in active development; acts on DLL4 and VEGFA.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2022
Kind
Antibody
Registered trials
5, 1 stopped early
Disease areas
Cancer; Hormones; Pregnancy and women's health; Urinary and reproductive; Digestive system; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Navicixizumab.

Targets

GeneProteinUniProt
VEGFAVascular endothelial growth factor A, long formP15692
DLL4Delta-like protein 4Q9NR61

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13201
Phase 21000
Phase 31000
All trials5

Who ran its trials

CompanyRoleYears
Mereo BioPharmaLead sponsor of trials2014 to now
OncXerna TheraputicsLead sponsor of trials2022 to now